Fatty liver disease, Liver failure

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Stem cells offer hope for recovery and symptom management in fatty liver disease and liver failure

Liver cells with fat droplets shown in yellow — illustration
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Stem cell treatment for Fatty liver disease, Liver failure

Fatty liver disease and hepatic insufficiency are conditions in which the liver is affected, which can result in a deterioration of liver function. These problems can be caused by several factors, including excessive alcohol consumption, obesity, viral infections and other health problems. Fatty liver disease and hepatic insufficiency can affect people of various ages and have serious consequences for liver health.

Our stem cell treatment for fatty liver disease and liver insufficiency involves direct administration of allogeneic mesenchymal stem cells to promote the repair of damaged liver tissues and improve liver health. This can lead to an improvement in liver function and an increased quality of life.

How is our stem cell treatment for Fatty Liver, Liver Insufficiency performed in Istanbul?

Both viruses cannot be spread through casual contact such as sharing utensils, kissing, hugging, or even coughing. However, it is advisable not to share personal items that could lead to blood contact. Research indicates that stem cell therapy may aid in the treatment of hepatitis B and C by regenerating liver function. Although the research was conducted on mice, human liver-derived stem cells were used in the mice. The results demonstrated that the stem cells could regenerate the liver to function normally and enhance survival rates.

Expert stem cell treatment led by Uzm. Dr. Cihan Bolat, MD

Under the leadership of Uzm. Dr. Cihan Bolat, MD, Specialist in Anaesthesiology and Reanimation · Regenerative Medicine, we provide expert treatments tailored to the unique needs of our patients. With our extensive experience and mesenchymal stem cells derived from umbilical cord tissue and Wharton’s jelly, and exosomes at our disposal, we offer an integrated approach to the treatment of Fatty Liver Disease, Liver Insufficiency. In our clinic we do not use performance-enhancing substances or components, and we strive for a relaxing atmosphere with a friendly and professional team to help you enjoy your stay.

A closer look

Fatty liver disease, Liver failure

Explore your topic. Discuss your questions and personal circumstances with us.

Discuss your situation
Fatty liver disease, Liver failure

How does our stem cell treatment for fatty liver disease, Liver failure work?

All our stem cell treatments in Istanbul are assessed and administered by specialists in the field, trained in the United States and Turkey, and not by general practitioners. We do this to ensure the highest level of precision, understanding of the condition and quality of treatment for our patients. We are 100% open and honest with our patients. Not everyone is eligible for our stem cell treatments.

We decline treatment for many patients after our specialist reviews their current health and medical history and determines that treatment is unsuitable. This avoids false promises or expectations when the risks outweigh the benefits. For this reason, and to ensure patient safety in all our treatments, each patient is assessed by the specialist before they can plan their treatment.

  1. Step 1.

    Specialist assessment

    For patients with Fatty Liver Disease, Liver Insufficiency, our specialist needs to know the patient's age and previous medical treatments. In addition, he will need to review the test results you will be asked to provide.

  2. Step 2.

    Free telephone consultation with the specialist

    Once the specialist has reviewed the medical records and confirmed your suitability, we will present treatment options and pricing. We also offer a free telephone consultation to discuss your questions and concerns.

  3. Step 3.

    Stem cell preparation

    Once you decide to undergo our treatment, we will send a deposit invoice to begin the process of stem cell preparation so that it is ready for your planned treatment. This process can take 5-10 days, depending on current demand and availability.

  4. Step 4.

    Treatment day

    On the day of treatment you can choose to come to our hospital location or use our free transportation to and from our clinic in Istanbul. Our driver will pick you up at your desired location and accompany you to our clinic, where the specialist will administer the treatment, and then take you safely back.

  5. Step 5.

    Follow-up care

    Our follow-up specialist will contact you according to our follow-up schedule to ensure you have all the resources you need for maximum benefits. Your well-being and satisfaction are our top priority.

Your life comes first

Time to talk. Space just for you.

Your questions, your wishes and your everyday life. That is where our conversation begins.

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Frequently asked questions

How effective is this stem cell treatment for Fatty Liver Disease, Liver Insufficiency?

Potential outcomes vary between people and treatment protocols. Your assessment should cover specific goals, the available research and the remaining uncertainties. Agree on when and how results will be assessed. Another patient’s experience cannot reliably predict your own outcome.

Include recent test results and your experience of previous treatments so that the assessment reflects your own situation.

Can Stem Cell Therapy Cure My Fatty Liver, Liver Insufficiency?

An improvement in symptoms is different from a cure. Whether stem cell therapy is a reasonable option for you depends on your diagnosis, previous treatment and the evidence for the proposed protocol. Discuss realistic goals and how progress would be measured; an individual outcome cannot be guaranteed.

Include recent test results and your experience of previous treatments so that the assessment reflects your own situation.

Which risks and side effects should I discuss?

Risks depend on the cell product, the administration method and your health. Ask the doctor to explain possible side effects and complications, how they would be managed and whom to contact after returning home. Injections and infusions are not risk-free.

What should I prepare for the consultation?

Write down your main symptoms and goals, and list your medication and previous treatments. Have recent medical reports available. During the initial contact, we can clarify which documents are needed and how to share them securely.

Research & insight

The science behind the possibilities.

Selected publications for Fatty liver disease, Liver failure

Fatty liver and liver insufficiency need separate assessment. The exosome research is preclinical; the patient study concerns hepatitis-B-related cirrhosis.

Preclinical · animal research2023

Exosomes and liver fat metabolism

In liver cells and mice, exosomes reduced fat accumulation through CAMKK1/AMPK signalling. This is mechanistic research, not a clinical fatty-liver treatment trial.

Exosomes / small extracellular vesicles from cord MSCs

Read on PubMedPMID 37274776
Study details
Reference
Yang F et al. JHEP Rep, 2023.
DOI: 10.1016/j.jhepr.2023.100746
Material studied
Exosomes / small extracellular vesicles from cord MSCs
Randomized trial2021

Long-term follow-up in liver cirrhosis

In 219 patients with hepatitis-B-related cirrhosis, liver function and survival improvements were reported. The study was unblinded; MSCs supplemented conventional treatment.

Umbilical cord tissue MSCs

Read on PubMedPMID 34843069
Study details
Reference
Shi M et al. Hepatol Int, 2021.
DOI: 10.1007/s12072-021-10199-2
Material studied
Umbilical cord tissue MSCs
How should you read these studies?

We select research by condition, cell source and administration, prioritising cord tissue and Wharton’s jelly. This is not a systematic review. A matching cell source does not mean preparation, dose or protocol matches our treatment. Extracellular vesicles, isolated exosomes and secretome are different preparations. Animal and laboratory research explores possible mechanisms; a trial protocol contains no results yet. PubMed inclusion is not treatment approval.

Sources checked: .

Relevance to your situation depends on diagnosis, product and treatment plan.

Discuss the research at your consultation

A personal journey. Support at every step.

From your first question to your return home. Explore the consultation, preparation and follow-up.

Understanding your situation
Understanding your situation
Step 01 — Getting to know you

It starts with your story.

Discuss your questions and the information needed for your evaluation. Your medical history and expectations are our starting point.

Start with your question
From proposal to travel
From proposal to travel
Step 02 — Preparing together

Plan your next step.

Discuss the treatment proposal, travel, accommodation and transfers. Agree on the practical arrangements before your visit.

Discuss your preparation
After your return
After your return
Step 03 — Care & follow-up

Attention that goes further.

Agree on treatment and follow-up arrangements, including whom to contact after you return home and which information to take with you.

Ask about follow-up care

Your first question is enough.

Ask about the treatment, costs or your journey. We can discuss what your next step might be.

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