Hip, knee and shoulder osteoarthritis

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Stem cells offer hope for recovery and symptom management

Knee joint with ligaments between the bones — illustration
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hip, knee and shoulder osteoarthritis

Stem cell treatment for hip, knee and shoulder osteoarthritis

Hip, knee and shoulder osteoarthritis are conditions in which the joints in these specific body parts deteriorate. This degeneration can occur due to various factors, such as natural aging, overuse or injury. Hip, knee and shoulder osteoarthritis can cause pain and discomfort and occurs in people of different ages. Our stem cell treatment for hip, knee and shoulder osteoarthritis involves direct administration of allogeneic mesenchymal stem cells to promote the repair of damaged joints in these specific body areas and improve joint health. This can lead to an improvement in the recovery process and an increased quality of life.

How is our stem cell treatment for hip, knee and shoulder Osteoarthritis performed in Istanbul?

Our regenerative treatments are led by Uzm. Dr. Cihan Bolat, MD, Specialist in Anaesthesiology and Reanimation · Regenerative Medicine. We use mesenchymal stem cells derived from umbilical cord tissue and Wharton’s jelly, and exosomes. Our medical team reviews each patient’s health and medical history to assess treatment suitability and discuss the available options.

Expert stem cell treatment led by Uzm. Dr. Cihan Bolat, MD

Under the leadership of Uzm. Dr. Cihan Bolat, MD, Specialist in Anaesthesiology and Reanimation · Regenerative Medicine, we provide expert treatments tailored to the unique needs of our patients. With our extensive experience and mesenchymal stem cells derived from umbilical cord tissue and Wharton’s jelly, and exosomes at our disposal, we offer an integrated approach to the treatment of hip, knee and shoulder osteoarthritis. In our clinic we do not use performance-enhancing substances or components, and we strive for a relaxing atmosphere with a friendly and professional team to help you enjoy your stay.

A closer look

Hip, knee and shoulder osteoarthritis

Explore your topic. Discuss your questions and personal circumstances with us.

Discuss your situation
Hip, knee and shoulder osteoarthritis

How does our stem cell treatment for hip, knee and shoulder osteoarthritis work?

All our stem cell treatments in Istanbul are assessed and administered by specialists in the field, trained in the United States and Turkey, and not solely by general practitioners. We do this to ensure the highest level of precision, understanding of the condition and quality of treatment for our patients. We are 100% open and honest with our patients. Not everyone is eligible for our stem cell treatments.

We decline treatment for many patients after our specialist reviews their current health and medical history and determines that treatment is unsuitable. This avoids false promises or expectations when the risks outweigh the benefits. For this reason, and to ensure patient safety in all our treatments, each patient is assessed by the specialist before they can plan their treatment.

  1. Step 1.

    Specialist assessment

    For patients with hip, knee and shoulder Osteoarthritis, our specialist needs to know the patient's age and previous medical treatments. In addition, he will need to review the test results you will be asked to provide.

  2. Step 2.

    Free telephone consultation with the specialist

    Once the specialist has reviewed the medical records and confirmed your suitability, we will present treatment options and pricing. We also offer a free telephone consultation to discuss your questions and concerns.

  3. Step 3.

    Stem cell preparation

    Once you decide to undergo our treatment, we will send a deposit invoice to begin the process of stem cell preparation so that it is ready for your planned treatment. This process can take 5-10 days, depending on current demand and availability.

  4. Step 4.

    Treatment day

    On the day of treatment you can choose to come to our hospital location or use our free transportation to and from our clinic in Istanbul. Our driver will pick you up at your desired location and accompany you to our clinic, where the specialist will administer the treatment, and then take you safely back.

  5. Step 5.

    Follow-up care

    Our follow-up specialist will contact you according to our follow-up schedule to ensure you have all the resources you need for maximum benefits. Your well-being and satisfaction are our top priority.

Your life comes first

What moves you? Our conversation starts there.

Your questions, your wishes and your everyday life. That is where our conversation begins.

Let’s get acquainted

Frequently asked questions

How effective is this stem cell treatment for hip, knee and shoulder osteoarthritis?

Potential outcomes vary between people and treatment protocols. Your assessment should cover specific goals, the available research and the remaining uncertainties. Agree on when and how results will be assessed. Another patient’s experience cannot reliably predict your own outcome.

Discuss pain, mobility and activity tolerance separately. Less pain does not automatically mean that cartilage, a tendon or other tissue has demonstrably regenerated.

How much does treatment cost, and what is included?

Costs depend on your assessment and the proposed treatment plan. Request an itemised quotation before making a decision.

The existing treatment information includes transport to and from the clinic, specialist treatment, a personal contact and follow-up. Confirm the exact arrangements in your quotation.

Before booking, request a written quotation covering treatment, tests, transport and follow-up. Confirm whether travel, accommodation, extra sessions and additional care are included. Insurance reimbursement is not automatic; check this with your insurer in advance.

Can stem cell therapy cure my hip, knee and shoulder osteoarthritis?

An improvement in symptoms is different from a cure. Whether stem cell therapy is a reasonable option for you depends on your diagnosis, previous treatment and the evidence for the proposed protocol. Discuss realistic goals and how progress would be measured; an individual outcome cannot be guaranteed.

Discuss pain, mobility and activity tolerance separately. Less pain does not automatically mean that cartilage, a tendon or other tissue has demonstrably regenerated.

How is my suitability assessed?

Medical assessment comes before treatment planning. Share your diagnosis, current symptoms, medication, previous treatments and available test results. The specialist considers potential benefits, risks and alternatives. Further assessment may be needed, and treatment may not be appropriate.

Research & insight

The science behind the possibilities.

Selected publications for Hip, knee and shoulder osteoarthritis

These studies focus on the knee. They do not provide direct clinical evidence of the same outcomes in the hip or shoulder.

Randomized trial2019

Repeated MSC injections for knee osteoarthritis

In this small trial, two injections reduced pain more than hyaluronic acid at twelve months. MRI scores did not differ; cartilage restoration was not demonstrated.

Umbilical cord tissue MSCs

Read on PubMedPMID 30592390
Study details
Reference
Matas J et al. Stem Cells Transl Med, 2019.
DOI: 10.1002/sctm.18-0053
Material studied
Umbilical cord tissue MSCs
Preclinical · animal research2022

Exosomes, cartilage and inflammatory cells

Exosomes reduced cartilage damage in rats and affected inflammatory cells in laboratory experiments. This investigates possible mechanisms, not efficacy in patients.

Exosomes / small extracellular vesicles from cord MSCs

Read on PubMedPMID 36267713
Study details
Reference
Li P et al. Ann Transl Med, 2022.
DOI: 10.21037/atm-22-3912
Material studied
Exosomes / small extracellular vesicles from cord MSCs
How should you read these studies?

We select research by condition, cell source and administration, prioritising cord tissue and Wharton’s jelly. This is not a systematic review. A matching cell source does not mean preparation, dose or protocol matches our treatment. Extracellular vesicles, isolated exosomes and secretome are different preparations. Animal and laboratory research explores possible mechanisms; a trial protocol contains no results yet. PubMed inclusion is not treatment approval.

Sources checked: .

Relevance to your situation depends on diagnosis, product and treatment plan.

Discuss the research at your consultation

A personal journey. Support at every step.

From your first question to your return home. Explore the consultation, preparation and follow-up.

Understanding your situation
Understanding your situation
Step 01 — Getting to know you

It starts with your story.

Discuss your questions and the information needed for your evaluation. Your medical history and expectations are our starting point.

Start with your question
From proposal to travel
From proposal to travel
Step 02 — Preparing together

Plan your next step.

Discuss the treatment proposal, travel, accommodation and transfers. Agree on the practical arrangements before your visit.

Discuss your preparation
After your return
After your return
Step 03 — Care & follow-up

Attention that goes further.

Agree on treatment and follow-up arrangements, including whom to contact after you return home and which information to take with you.

Ask about follow-up care

Your first question is enough.

Ask about the treatment, costs or your journey. We can discuss what your next step might be.

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