Hair restoration

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Stem cells offer hope for recovery and symptom management in Hair Restoration

Hair follicles beneath the skin surface — illustration
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Stem cell treatment for Hair restoration

Hair restoration refers to procedures and treatments aimed at promoting growth, strengthening and restoring healthy hair in people dealing with hair loss, thinning hair or other hair problems. These treatments can range from medical procedures and medications to cosmetic procedures and hair care products. People often seek hair restoration treatments to regain their confidence and achieve a fuller head of hair.

How is our stem cell treatment for Hair Restoration performed in Istanbul?

At Istanbul Stamcel, we use PRP (platelet-rich plasma), mesenchymal stem cells derived from Wharton’s jelly, and exosomes derived from those mesenchymal stem cells for hair restoration. Wharton’s jelly is the connective tissue within the umbilical cord. PRP, stem cells and exosomes are distinct products, each with its own role in the personalised treatment plan.

For PRP, a small amount of your own blood is collected and processed to obtain platelet-rich plasma. This is administered through targeted injections into the scalp. Platelets release growth factors involved in cell activity and tissue repair. The treatment aims to support the scalp and existing hair follicles. Your doctor explains how the mesenchymal stem cells and their derived exosomes are used and administered within your treatment plan.

Before treatment, your doctor assesses the cause of your hair loss, the condition of your scalp and your medical history to determine a suitable approach. Possible side effects, such as temporary tenderness, redness or swelling after injections, are discussed beforehand. Results vary between individuals and treatment components.

Expert stem cell treatment led by Uzm. Dr. Cihan Bolat, MD

Under the leadership of Uzm. Dr. Cihan Bolat, MD, Specialist in Anaesthesiology and Reanimation · Regenerative Medicine, we provide expert treatments tailored to the unique needs of our patients. With our extensive experience and mesenchymal stem cells derived from umbilical cord tissue and Wharton’s jelly, and exosomes at our disposal, we offer an integrated approach to the treatment of Hair Restoration. In our clinic we do not use performance-enhancing substances or components, and we strive for a relaxing atmosphere with a friendly and professional team to help you enjoy your stay.

A closer look

Hair restoration

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Discuss your situation
Hair restoration

How does our stem cell treatment for hair restoration work?

All our stem cell treatments in Istanbul are assessed and administered by specialists in the field, trained in the United States and Turkey, and not solely by general practitioners. We do this to ensure the highest level of precision, understanding of the condition and quality of treatment for our patients. We are 100% open and honest with our patients. Not everyone is eligible for our stem cell treatments.

We decline treatment for many patients after our specialist reviews their current health and medical history and determines that treatment is unsuitable. This avoids false promises or expectations when the risks outweigh the benefits. For this reason, and to ensure patient safety in all our treatments, each patient is assessed by the specialist before they can plan their treatment.

  1. Step 1.

    Specialist assessment

    For Hair Restoration patients, our specialist will need to know the patient's age and previous medical treatments. In addition, he will need to review the test results you will be asked to provide.

  2. Step 2.

    Free telephone consultation with the specialist

    Once the specialist has reviewed the medical records and confirmed your suitability, we will present treatment options and pricing. We also offer a free telephone consultation to discuss your questions and concerns.

  3. Step 3.

    Stem cell preparation

    Once you decide to undergo our treatment, we will send a deposit invoice to begin the process of stem cell preparation so that it is ready for your planned treatment. This process can take 5-10 days, depending on current demand and availability.

  4. Step 4.

    Treatment day

    On the day of treatment you can choose to come to our hospital location or use our free transportation to and from our clinic in Istanbul. Our driver will pick you up at your desired location and accompany you to our clinic, where the specialist will administer the treatment, and then take you safely back.

  5. Step 5.

    Follow-up care

    Our follow-up specialist will contact you according to our follow-up schedule to ensure you have all the resources you need for maximum benefits. Your well-being and satisfaction are our top priority.

Your life comes first

Time to talk. Space just for you.

Your questions, your wishes and your everyday life. That is where our conversation begins.

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Frequently asked questions

Which risks and side effects should I discuss?

Risks depend on the cell product, the administration method and your health. Ask the doctor to explain possible side effects and complications, how they would be managed and whom to contact after returning home. Injections and infusions are not risk-free.

How much does treatment cost, and what is included?

Costs depend on your assessment and the proposed treatment plan. Request an itemised quotation before making a decision.

The existing treatment information includes transport to and from the clinic, specialist treatment, a personal contact and follow-up. Confirm the exact arrangements in your quotation.

Before booking, request a written quotation covering treatment, tests, transport and follow-up. Confirm whether travel, accommodation, extra sessions and additional care are included. Insurance reimbursement is not automatic; check this with your insurer in advance.

How effective is this stem cell treatment for hair restoration?

Potential outcomes vary between people and treatment protocols. Your assessment should cover specific goals, the available research and the remaining uncertainties. Agree on when and how results will be assessed. Another patient’s experience cannot reliably predict your own outcome.

First discuss the cause of hair loss and the difference between hair transplantation and an additional cell treatment. Their goals and assessment are different.

How is my suitability assessed?

Medical assessment comes before treatment planning. Share your diagnosis, current symptoms, medication, previous treatments and available test results. The specialist considers potential benefits, risks and alternatives. Further assessment may be needed, and treatment may not be appropriate.

Research & insight

The science behind the possibilities.

Selected publications for Hair restoration

Explore what was actually studied and how the findings relate to this treatment.

Systematic review2025

Clinical research on exosomes and hair growth

This review of eleven studies found early positive signals for hair growth. Sources and methods varied considerably; findings do not automatically apply to one cord-derived product.

Various exosome sources and preparations

Read on PubMedPMID 40955427
Study details
Reference
Al Ameer MA et al. Clin Cosmet Investig Dermatol, 2025.
DOI: 10.2147/ccid.s543451
Material studied
Various exosome sources and preparations
Preclinical · animal research2024

Cord-derived exosomes and hair follicles

An exosome gel promoted hair growth in a mouse model involving RAS/ERK signalling. Human hair transplantation and graft survival were not studied.

Exosomes / small extracellular vesicles from cord MSCs

Read on PubMedPMID 39513036
Study details
Reference
Mao Y et al. J Transl Int Med, 2024.
DOI: 10.1515/jtim-2024-0012
Material studied
Exosomes / small extracellular vesicles from cord MSCs
Trial protocol · no results2026

A planned trial in hereditary hair loss

This protocol describes testing small extracellular vesicles from cord MSCs against minoxidil. It contains a research plan, not treatment results.

Exosomes / small extracellular vesicles from cord MSCs

Read on PubMedPMID 41591820
Study details
Reference
Tian R et al. FASEB J, 2026.
DOI: 10.1096/fj.202504430
Material studied
Exosomes / small extracellular vesicles from cord MSCs
How should you read these studies?

We select research by condition, cell source and administration, prioritising cord tissue and Wharton’s jelly. This is not a systematic review. A matching cell source does not mean preparation, dose or protocol matches our treatment. Extracellular vesicles, isolated exosomes and secretome are different preparations. Animal and laboratory research explores possible mechanisms; a trial protocol contains no results yet. PubMed inclusion is not treatment approval.

Sources checked: .

Relevance to your situation depends on diagnosis, product and treatment plan.

Discuss the research at your consultation

A personal journey. Support at every step.

From your first question to your return home. Explore the consultation, preparation and follow-up.

Understanding your situation
Understanding your situation
Step 01 — Getting to know you

It starts with your story.

Discuss your questions and the information needed for your evaluation. Your medical history and expectations are our starting point.

Start with your question
From proposal to travel
From proposal to travel
Step 02 — Preparing together

Plan your next step.

Discuss the treatment proposal, travel, accommodation and transfers. Agree on the practical arrangements before your visit.

Discuss your preparation
After your return
After your return
Step 03 — Care & follow-up

Attention that goes further.

Agree on treatment and follow-up arrangements, including whom to contact after you return home and which information to take with you.

Ask about follow-up care

Your first question is enough.

Ask about the treatment, costs or your journey. We can discuss what your next step might be.

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